NEDPA EPE Ephenidine NEDPA EPE Ephenidine NEDPA EPE Ephenidine

Model: top grade
Place of Origin: Jiangsu,China (Mainland)
Brand Name: yuechem
CAS No.: 60951-19-1
Purity: >99%
white powder: raw material


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Product Description

Payment & Shipping Terms Supply Capacity
Unit Price:2.0 USDProduction Capacity:800kg/month
Trade Term:FOBPacking:Aluminum foil...
Payment Terms:WU, Money Gram, bitcoinDelivery Date:24h after the payment
Min. Order:1 Gram
Means of Transport:Land, Ocean, Air


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Ephenidine (also known as NEDPA and EPE) is a dissociative anesthetic that has been sold online as a designer drug. It is illegal in some countries as a structural isomer of the banned opioid drug lefetamine, but has been sold in countries where it is not yet banned.

Ephenidine and related diarylethylamines have been studied in vitro as treatments for neurotoxic injuries, and are antagonists of the NMDA receptor. Ephenidine also possesses substantially weaker affinity for dopamine and norepinephrine transporters (379 nM and 841 nM, respectively) as well as σ1R (629 nM) and σ2R (722 nM) binding sites.

Ephenidines metabolic pathway consists of N-oxidation, N-dealkylation, mono- and bis-hydroxylation of the benzene ring, and hydroxylation of the phenyl ring only after N-dealkylation. The dihydroxy metabolites were conjugated by methylation of one hydroxy group, and hydroxy metabolites by glucuronidation or sulfation.

Ephenidine reacts with reagent tests to give a semi-unique array of colors which can be used to aid its identification.

Category: Research chemical

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